Phazon

Phazon, is a highly radioactive and hallucinogenic drug originating from PHAAAAAAAAAAAAAAAAAZE, and is shipped off by giant freaking meteors to unsuspecting planets. As of right now, the largest drug lord supplying it is Dank Samus. Phazon can give life, and can also BALEET life. It is eventually outlawed by the Galatactic Federation, and yet they use it as fuel and weapons later.

Usage
Phazon is a McGuffin to heart, and can do whatever the plot requires it to do, be it a Boss Battle creator, Hazard, whatever. It serves as the second greatest plot mechanic, right behind you-know-what.